The therapeutic potential of RNA interference.

@article{Uprichard2005TheTP,
  title={The therapeutic potential of RNA interference.},
  author={Susan L. Uprichard},
  journal={FEBS letters},
  year={2005},
  volume={579 26},
  pages={5996-6007}
}
In recent years, we have witnessed the discovery of a new mechanism of gene regulation called RNA interference (RNAi), which has revitalized interest in the development of nucleic acid-based technologies for therapeutic gene suppression. This review focuses on the potential therapeutic use of RNAi, discussing the theoretical advantages of RNAi-based therapeutics over previous technologies as well as the challenges involved in developing RNAi for clinical use. Also reviewed, are the in vivo… CONTINUE READING

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