The therapeutic monitoring of antimicrobial agents.

@article{Begg1999TheTM,
  title={The therapeutic monitoring of antimicrobial agents.},
  author={Evan James Begg and Murray Lindsay Barclay and Carl M. J. Kirkpatrick},
  journal={British journal of clinical pharmacology},
  year={1999},
  volume={47 1},
  pages={23-30}
}
AIMS To review the basis and optimal use of therapeutic drug monitoring of antimicrobial agents. METHODS Antimicrobial agents for which a reasonable case exists for therapeutic drug monitoring were reviewed under the following headings: pharmacokinetics, why monitor, therapeutic range, individualisation of therapy, sampling times, methods of analysis, interpretative problems and cost-effectiveness of monitoring. RESULTS There is a strong historical case for monitoring aminoglycosides. The… CONTINUE READING

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