The therapeutic efficacy of human adipose tissue-derived mesenchymal stem cells on experimental autoimmune hearing loss in mice.

@article{Zhou2011TheTE,
  title={The therapeutic efficacy of human adipose tissue-derived mesenchymal stem cells on experimental autoimmune hearing loss in mice.},
  author={Yixuan Zhou and Jingdong Yuan and Bin Zhou and Austin J Lee and Albert J Lee and Maher Ghawji and T. Yoo},
  journal={Immunology},
  year={2011},
  volume={133 1},
  pages={133-40}
}
Autoimmune inner ear disease is characterized by progressive, bilateral although asymmetric, sensorineural hearing loss. Patients with autoimmune inner ear disease had higher frequencies of interferon-γ-producing T cells than did control subjects tested. Human adipose-derived mesenchymal stem cells (hASCs) were recently found to suppress effector T cells and inflammatory responses and therefore have beneficial effects in various autoimmune diseases. The aim of this study was to examine the… CONTINUE READING
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