The temptation of suicide: striatal gray matter, discounting of delayed rewards, and suicide attempts in late-life depression.

@article{Dombrovski2012TheTO,
  title={The temptation of suicide: striatal gray matter, discounting of delayed rewards, and suicide attempts in late-life depression.},
  author={Alexandre Y Dombrovski and Greg J. Siegle and Katalin Szanto and Luke Clark and Charles F. Reynolds and Howard Aizenstein},
  journal={Psychological medicine},
  year={2012},
  volume={42 6},
  pages={1203-15}
}
BACKGROUND Converging evidence implicates basal ganglia alterations in impulsivity and suicidal behavior. For example, D2/D3 agonists and subthalamic nucleus stimulation in Parkinson's disease (PD) trigger impulse control disorders and possibly suicidal behavior. Furthermore, suicidal behavior has been associated with structural basal ganglia abnormalities. Finally, low-lethality, unplanned suicide attempts are associated with increased discounting of delayed rewards, a behavior dependent upon… CONTINUE READING
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