The temperature dependence of lipid membrane permeability, its quantized nature, and the influence of anesthetics.

@article{Blicher2009TheTD,
  title={The temperature dependence of lipid membrane permeability, its quantized nature, and the influence of anesthetics.},
  author={A. Peter Blicher and Katarzyna Wodzińska and Matthias Fidorra and Mathias Winterhalter and Thomas Heimburg},
  journal={Biophysical journal},
  year={2009},
  volume={96 11},
  pages={4581-91}
}
We investigate the permeability of lipid membranes for fluorescence dyes and ions. We find that permeability reaches a maximum close to the chain melting transition of the membranes. Close to transitions, fluctuations in area and compressibility are high, leading to an increased likelihood of spontaneous lipid pore formation. Fluorescence correlation spectroscopy reveals the permeability for rhodamine dyes across 100-nm vesicles. Using fluorescence correlation spectroscopy, we find that the… CONTINUE READING
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Ion channel s. (http://membranes.nbi.dk/ Kaufmann/ pdf/ Kaufmann book3ed.pdf), Caruaru

  • K. Kaufmann, W. Hanke, A. Corcia
  • 1989
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