The targeted delivery of anticancer drugs to brain glioma by PEGylated oxidized multi-walled carbon nanotubes modified with angiopep-2.

@article{Ren2012TheTD,
  title={The targeted delivery of anticancer drugs to brain glioma by PEGylated oxidized multi-walled carbon nanotubes modified with angiopep-2.},
  author={Jinfeng Ren and Shun Quan Shen and Dangge Wang and Zhangjie Xi and Liangran Guo and Zhiqing Pang and Yong Qian and Xiyang Sun and Xinguo Jiang},
  journal={Biomaterials},
  year={2012},
  volume={33 11},
  pages={
          3324-33
        }
}
In this study, a dual-targeting drug delivery system based on PEGylated oxidized multi-walled carbon nanotubes (O-MWNTs) modified with angiopep-2 (O-MWNTs-PEG-ANG) was successfully developed for treatment of brain glioma. O-MWNTs can not only distribute in brains but also accumulate in tumors, and have ultrahigh surface area with remarkably high loading anticancer drug of doxorubicin (DOX), which was selected as drug carrier. Angiopep-2 can specifically combine to the low-density lipoprotein… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 90 CITATIONS

FILTER CITATIONS BY YEAR

2012
2019

CITATION STATISTICS

  • 5 Highly Influenced Citations

  • Averaged 12 Citations per year over the last 3 years

References

Publications referenced by this paper.
SHOWING 1-10 OF 43 REFERENCES

Similar Papers

Loading similar papers…