The tachykinin NK1 receptor mediates the migration-promoting effect of substance P on human skin fibroblasts in culture


Fibroblast migration is an important component of the tissue response during the repair process, and substance P (SP) has been shown to exert trophic effects. In the present study, cell migration was evaluated as the distance travelled by adherent human skin fibroblasts (HF) at 96 h and by the number of individual cells moving across a filter within 5 h. In… (More)
DOI: 10.1007/BF00169165


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