The tachykinin NK1 receptor in the brain: pharmacology and putative functions.

  • Alois Saria
  • Published 1999 in European journal of pharmacology


After its discovery in 1931, substance P (SP) remained the only mammalian member of the family of tachykinin peptides for several decades. Tachykinins thus refer to peptides sharing the common C-terminal amino acid sequence Phe-X-Gly-Leu-Met x NH2. In recent years the family of mammalian tachykinins has grown with the isolation of two novel peptides from… (More)


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