The systolic hypertension in the elderly program

  title={The systolic hypertension in the elderly program},
  author={H. Mitchell Perry and Kenneth G. Berge and M. Donald Blaufox and Barry R. Davis and Richard H. Grimm and Robert H. McDonald and Sara L. Pressel and Eleanor B Schron and William M. Smith and Thomas M. Vogt},
The Systolic Hypertension in the Elderly Program (SHEP) was a randomized multicenter double-blind placebo-controlled trial designed to test the efficacy of antihypertensive drug treatment in persons 60 years of age or older who had isolated systolic hypertension (ISH). ISH was defined as a systolic blood pressure (SBP) (160–219 mmHg) and a diastolic blood pressure (DBP) (< 90 mmHg). Prior to the completion of SHEP, ISH remained the most important unresolved therapeutic problem involving… CONTINUE READING