The systemic beta-adrenergic pathway to renin secretion: relationships with the renal prostaglandin system.

@article{Henrich1983TheSB,
  title={The systemic beta-adrenergic pathway to renin secretion: relationships with the renal prostaglandin system.},
  author={William L. Henrich and William Campbell},
  journal={Endocrinology},
  year={1983},
  volume={113 6},
  pages={2247-54}
}
The relationship between renin release evoked by circulating beta-agonists and the renal prostaglandin (PG) system is incompletely defined. Thus, we evaluated systemic and renal hemodynamic responses to iv (0.5 micrograms/kg X min) and intrarenal arterial (0.6 micrograms/kg X min) infusions of the beta1-agonist prenalterol (PNL) in four separate groups of anesthetized dogs. Consecutive iv PNL infusions (n = 6) resulted in a reversible decrease in mean arterial pressure (130 to 117 mm Hg; P less… CONTINUE READING