The systemic availability of oral glutathione

  title={The systemic availability of oral glutathione},
  author={Anne Witschi and Sunil Reddy and Bruce C Stofer and Bernhard H. Lauterburg},
  journal={European Journal of Clinical Pharmacology},
SummaryWhen the plasma glutathione concentration is low, such as in patients with HIV infection, alcoholics, and patients with cirrhosis, increasing the availability of circulating glutathione by oral administration might be of therapeutic benefit.To assess the feasibility of supplementing oral glutathione we have determined the systemic availability of glutathione in 7 healthy volunteers.The basal concentrations of glutathione, cysteine, and glutamate in plasma were 6.2, 8.3, and 54 μmol·l−1… 

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