The systemic amyloidoses: clearer understanding of the molecular mechanisms offers hope for more effective therapies.

@article{Merlini2004TheSA,
  title={The systemic amyloidoses: clearer understanding of the molecular mechanisms offers hope for more effective therapies.},
  author={Giampaolo Merlini and Per Westermark},
  journal={Journal of internal medicine},
  year={2004},
  volume={255 2},
  pages={159-78}
}
Knowledge about the systemic amyloidoses has increased considerably during the last few years. This group of diseases is characterized by great biochemical variability, including at least 11 different amyloid fibril proteins and a remarkable range of clinical manifestations. With the understanding that the pathogenesis is different in the various forms of amyloidosis, it is now being increasingly accepted that an early and accurate diagnosis, including that of the underlying biochemical nature… CONTINUE READING