The synthetic prostaglandin E1 analogue rioprostil reduces the nephrotoxic potential of cyclosporine A.

Abstract

Acute CyA nephrotoxicity involves alteration in the proximal tubule and leads to glomerular lesions. Administration of a vasodilatator agent such as the prostaglandin E1 analogue Rioprostil (Bayer AG, BAY 06893) might prevent preglomerular vasoconstriction and hence reduce cyclosporin nephrotoxicity. As an increased excretion of urinary enzymes as a… (More)

Topics

Cite this paper

@article{MetzKurschel1990TheSP, title={The synthetic prostaglandin E1 analogue rioprostil reduces the nephrotoxic potential of cyclosporine A.}, author={Ulrike Metz-Kurschel and K B Wagner and Michael Karl Mueller}, journal={Transplantation proceedings}, year={1990}, volume={22 4}, pages={1713-6} }