The synthetic cannabinoid Spice as a trigger for an acute exacerbation of cannabis induced recurrent psychotic episodes

  title={The synthetic cannabinoid Spice as a trigger for an acute exacerbation of cannabis induced recurrent psychotic episodes},
  author={Helge H. M{\"u}ller and Wolfgang Sperling and Martin Köhrmann and Hagen B. Huttner and Johannes Kornhuber and Juan Manuel Maler},
  journal={Schizophrenia Research},
Synthetic cannabinoid induced psychosis in a previously nonpsychotic patient.
This case report examines the acute psychosis displayed by a psychiatric patient after smoking “Spice,” a substance comprised of various synthetic cannabinoids, on three separate occasions and explores the possibility that synthetic cannabinoids are more potent than their organic counterpart.
Psychotic Disorder Associated With Synthetic Cannabinoid Receptor Agonists : A Case Report 2
A case of a rare psychotic disorder that developed following repeated use of SCRA and its treatment are presented.
Psychosis and synthetic cannabinoids
Substance-Induced Psychoses: An Updated Literature Review
The theory that psychosis due to substance abuse is commonly observed in clinical practice is supported, and the propensity to develop psychosis seems to be a function of the severity of use and addiction.
Psychotic Disorders in Patients Who Use Synthetic Cannabinoids
The study revealed that psychotic symptoms are typical manifestations in association with intoxication with synthetic cannabinoids, and several nonspecific characteristics of the psychoses that may occur in patients intoxicated with synthetic cannabinoid use are identified.
[Clinical variants of psychoses in patients using synthetic cannabinoids (Spice)].
Clinical and differential diagnostic characteristics of four clinical variants with predominant delirious symptoms or hallucinatory symptoms or affective-delusions developed due to synthetic cannabinoids (Spice) are described.
Gone to Pot – A Review of the Association between Cannabis and Psychosis
The evidence indicates that cannabis may be a component cause in the emergence of psychosis, and this warrants serious consideration from the point of view of public health policy.
Ischemic stroke associated with the use of a synthetic cannabinoid (spice).


Effects of cannabidiol on schizophrenia-like symptoms in people who use cannabis
Hair samples were analysed to examine levels of Δ9-THC and CBD in 140 individuals and three clear groups emerged: ’THC only’, ‘THC+CBD’ and those with no cannabinoid in hair, which provides evidence of the divergent properties of cannabinoids.
Cannabis and schizophrenia: towards a cannabinoid hypothesis of schizophrenia
There is a complex interaction between the dopaminergic and the endocannabinoid receptor system and agents that interact with the cannabinoid receptor system, such as the nonpsychoactive cannabidiol, might be beneficial in the treatment of psychosis.
Cannabis-related psychosis and the gene-environment interaction: comments on Ferdinand et Al. 2005.
It is shown that the genetic factors that influence the sensitivity to the psychosis-increasing effects of cannabis may also influence the probability that individuals will start using cannabis in the first place, and the commonly reported simultaneous existence of not only gene–environment interaction but also gene-environment correlation in the causation of psychiatric phenotypes may apply similarly to the relationship between cannabis and psychosis.
Cannabis use and risk of psychotic or affective mental health outcomes: a systematic review
Case report 3
An unusual case of RAG2 gene mutation induced PID presenting clinically as severe combined immunodeficiency (SCID) phenotype rather than Ommen’s syndrome, and acquired CMV infection via breast milk is described.
Synthesis and pharmacology of 1-deoxy analogs of CP-47,497 and CP-55,940.
2005.Cannabis-relatedpsychosis and thegene– environment interaction: comments on
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