The synthesis of the two S-adenosyl-methionine synthetases is differently regulated in Saccharomyces cerevisiae

@article{Thomas1991TheSO,
  title={The synthesis of the two S-adenosyl-methionine synthetases is differently regulated in Saccharomyces cerevisiae},
  author={Dominique Thomas and Yolande Surdin-Kerjan},
  journal={Molecular and General Genetics MGG},
  year={1991},
  volume={226},
  pages={224-232}
}
S-adenosyl-l-methionine (AdoMet) is synthesized by transfer of the adenosyl moiety of ATP to the sulfur atom of methionine. This reaction is catalysed by AdoMet synthetase. In all eukaryotic organisms studied so far, multiple forms of AdoMet synthetases have been reported and from their recent study, it appears that AdoMet synthetase is an exceptionally well conserved enzyme through evolution. In Saccharomyces cerevisiae, we have demonstrated the existence of two AdoMet synthetases encoded by… CONTINUE READING

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