The synthesis of indanones related to combretastatin A-4 via microwave- assisted Nazarov cyclization of chalcones


Our research groups have a long-standing interest in anticancer agents, especially those derived from natural products. In 1996, as part of a plant-screening program, we identified Scutellaria barbata D. Don ( Labiatae ) as a potential source of anticancer agents. The dried whole plant, readily available from herb wholesalers, is used in traditional Chinese… (More)