The synthesis of CP-195543, an LTB4 antagonist for the treatment of inflammatory diseases.

@article{Caron1999TheSO,
  title={The synthesis of CP-195543, an LTB4 antagonist for the treatment of inflammatory diseases.},
  author={St{\'e}phane Caron},
  journal={Current opinion in drug discovery & development},
  year={1999},
  volume={2 6},
  pages={550-6}
}
  • Stéphane Caron
  • Published 1999 in Current opinion in drug discovery & development
A review of the process research and development of CP-195543 is presented. This chronological depiction from the original medicinal chemistry synthesis, which yielded a few grams of final product, to a novel route which allowed the compound to be prepared in multi-kilogram quantities, demonstrates some of the challenges which pace environment. This project… CONTINUE READING