The synthesis and pharmacological evaluation of adamantane-derived indoles: cannabimimetic drugs of abuse.

@article{Banister2013TheSA,
  title={The synthesis and pharmacological evaluation of adamantane-derived indoles: cannabimimetic drugs of abuse.},
  author={S. Banister and Shane M. Wilkinson and Mitchell Longworth and J. Stuart and Nadine Apetz and Katrina English and L. Brooker and C. Goebel and D. Hibbs and M. Glass and M. Connor and I. McGregor and M. Kassiou},
  journal={ACS chemical neuroscience},
  year={2013},
  volume={4 7},
  pages={
          1081-92
        }
}
Two novel adamantane derivatives, adamantan-1-yl(1-pentyl-1H-indol-3-yl)methanone (AB-001) and N-(adamtan-1-yl)-1-pentyl-1H-indole-3-carboxamide (SDB-001), were recently identified as cannabimimetic indoles of abuse. Conflicting anecdotal reports of the psychoactivity of AB-001 in humans, and a complete dearth of information about the bioactivity of SDB-001, prompted the preparation of AB-001, SDB-001, and several analogues intended to explore preliminary structure-activity relationships within… Expand
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