The synthesis and aqueous superoxide anion scavenging of water-dispersible lutein esters.

@article{Nadolski2006TheSA,
  title={The synthesis and aqueous superoxide anion scavenging of water-dispersible lutein esters.},
  author={Geoff Nadolski and Arturo J. Cardounel and Jay L. Zweier and Samuel F. Lockwood},
  journal={Bioorganic \& medicinal chemistry letters},
  year={2006},
  volume={16 4},
  pages={
          775-81
        }
}
View on PubMed
doi.org
16 Citations
Highly Influential Citations
3
Background Citations
7
Methods Citations
1

16 Citations

Association studies of aggregated aqueous lutein diphosphate with human serum albumin and alpha1-acid glycoprotein in vitro: evidence from circular dichroism and electronic absorption spectroscopy.

Incorporation of bixin in aqueous media: Self-formulation with sorbitol ester of norbixin.

Cucurbitacin glucosides: antioxidant and free-radical scavenging activities.

Optimization of the ultrasound-assisted synthesis of lutein disuccinate using uniform design.

Nutritionally important carotenoids as consumer products

Abstract Carotenoids are nutritionally-beneficial organic tetraterpenoid pigments synthesized mainly by plants, bacteria and fungi. Although research has focused on the production of carotenoids in…

The first synthesis of PEG-carotenoid conjugates

Preparation and Corresponding Properties of a Novel Aqueous Derivative of Lutein

The disulfosuccinate sodium salt of lutein (Ldss) was prepared for the first time and an obvious blue shift appeared in the UV absorption spectra of its aqueous solution due to the formation of sub...

Carotenoids as Novel Therapeutic Molecules Against Neurodegenerative Disorders: Chemistry and Molecular Docking Analysis

It is shown that carotenoids are powerful anti-amyloidogenic molecules with a potential role in preventing AD, especially since most of them can cross the blood-brain barrier and are considered nutraceutical compounds.

Purification of synthetic all-E lycophyll (ψ,ψ-carotene-16,16′-diol)

Hydrophilic Carotenoids: Recent Progress

This review compiles the recently synthetized hydrophilic carotenoid derivatives and investigates their applications in medicine and food chemistry.

References

SHOWING 1-10 OF 29 REFERENCES

Synthesis, characterization, and direct aqueous superoxide anion scavenging of a highly water-dispersible astaxanthin-amino acid conjugate.

Direct superoxide anion scavenging by a disodium disuccinate astaxanthin derivative: Relative efficacy of individual stereoisomers versus the statistical mixture of stereoisomers by electron paramagnetic resonance imaging.

Direct superoxide anion scavenging by a highly water-dispersible carotenoid phospholipid evaluated by electron paramagnetic resonance (EPR) spectroscopy.

In vitro plasma protein binding and aqueous aggregation behavior of astaxanthin dilysinate tetrahydrochloride.

Interaction of the disodium disuccinate derivative of meso-astaxanthin with human serum albumin: from chiral complexation to self-assembly.

Plasma appearance and tissue accumulation of non-esterified, free astaxanthin in C57BL/6 mice after oral dosing of a disodium disuccinate diester of astaxanthin (Heptax).

Chiral detection of carotenoid assemblies.

UV/VIS and CD spectroscopy revealed the formation of J- and H-types of aggregates of both right- and left-handed kinds and a hypothetical structure for H-type assemblies is proposed.

Bioactive carotenoids: potent antioxidants and regulators of gene expression

The ability to deliver biologically active carotenoids at high concentration and with good reproducibility appears to have been achieved and antineoplastic potential is suggested.

Investigation of the Self-Organization of Lutein and Lutein Diacetate by Electronic Absorption, Circular Dichroism Spectroscopy, and Atomic Force Microscopy

Spontaneously forming H- and J-type chiral self-assemblies of lutein and lutein diacetate were studied by means of ultraviolet−visible and circular dichroism spectroscopy (CD). Spectroscopic…

The Efficient Synthesis of Disodium Disuccinate Astaxanthin (Cardax)

A practical procedure is described for the multigram preparation of disodium disuccinate derivatives of synthetic astaxanthin (Cardax) [from all-trans-(all-E)-3S,3‘S-, meso-(3R,3‘S)-, and…