The synergistic effect of IFN-α and IFN-γ against HSV-2 replication in Vero cells is not interfered by the plant antiviral 1-cinnamoyl-3, 11-dihydroxymeliacarpin

@article{Petrera2006TheSE,
  title={The synergistic effect of IFN-α and IFN-γ against HSV-2 replication in Vero cells is not interfered by the plant antiviral 1-cinnamoyl-3, 11-dihydroxymeliacarpin},
  author={Erina Petrera and Celia E. Coto},
  journal={Virology Journal},
  year={2006},
  volume={3},
  pages={45 - 45}
}
Recent studies have shown that gamma interferon (IFN-γ) synergizes with IFN-α/β to inhibit herpes simplex virus type 1 (HSV-1) replication in vitro. Since IFN response represents an early host defense event against viral infection and the fact that treatment with meliacine, a plant antiviral, ameliorate the severity of the herpetic infection in female mice infected intravaginally with HSV-2, we wanted to investigate whether the administration of meliacine to HSV-2 infected mice could altered… CONTINUE READING
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Efectos de la administración in vivo del antiviral meliacina sobre el curso de la infección herpética genital murina [abstract

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2 Excerpts

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