The synergetic effect of hydrogel stiffness and growth factor on osteogenic differentiation.

@article{Tan2014TheSE,
  title={The synergetic effect of hydrogel stiffness and growth factor on osteogenic differentiation.},
  author={Shihjye Tan and Josephine Y. Fang and Zhi Yang and Marcel E. Nimni and Bo Han},
  journal={Biomaterials},
  year={2014},
  volume={35 20},
  pages={5294-306}
}
Cells respond to various chemical signals as well as environmental aspects of the extracellular matrix (ECM) that may alter cellular structures and functions. Hence, better understanding of the mechanical stimuli of the matrix is essential for creating an adjuvant material that mimics the physiological environment to support cell growth and differentiation, and control the release of the growth factor. In this study, we utilized the property of transglutaminase cross-linked gelatin (TG-Gel… CONTINUE READING
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