The synaptic vesicle protein SV2 is complexed with an alpha5-containing laminin on the nerve terminal surface.

@article{Son2000TheSV,
  title={The synaptic vesicle protein SV2 is complexed with an alpha5-containing laminin on the nerve terminal surface.},
  author={Young Jin Son and T W Scranton and William J. Sunderland and S J Baek and Jeffrey H Miner and Joshua R Sanes and Steven S. Carlson},
  journal={The Journal of biological chemistry},
  year={2000},
  volume={275 1},
  pages={451-60}
}
Interactions between growing axons and synaptic basal lamina components direct the formation of neuromuscular junctions during nerve regeneration. Isoforms of laminin containing alpha5 or beta2 chains are potential basal lamina ligands for these interactions. The nerve terminal receptors are unknown. Here we show that SV2, a synaptic vesicle transmembrane proteoglycan, is complexed with a 900-kDa laminin on synaptosomes from the electric organ synapse that is similar to the neuromuscular… CONTINUE READING

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