The synaptic vesicle cycle.
@article{Sudhof2004TheSV, title={The synaptic vesicle cycle.}, author={T. Sudhof}, journal={Annual review of neuroscience}, year={2004}, volume={27}, pages={ 509-47 } }
Neurotransmitter release is mediated by exocytosis of synaptic vesicles at the presynaptic active zone of nerve terminals. To support rapid and repeated rounds of release, synaptic vesicles undergo a trafficking cycle. The focal point of the vesicle cycle is Ca2+-triggered exocytosis that is followed by different routes of endocytosis and recycling. Recycling then leads to the docking and priming of the vesicles for another round of exo- and endocytosis. Recent studies have led to a better… Expand
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