The sympathetic nerve--an integrative interface between two supersystems: the brain and the immune system.

@article{Elenkov2000TheSN,
  title={The sympathetic nerve--an integrative interface between two supersystems: the brain and the immune system.},
  author={Ilia J. Elenkov and Ronald L. Wilder and George P. Chrousos and E. Sylvester Vizi},
  journal={Pharmacological reviews},
  year={2000},
  volume={52 4},
  pages={595-638}
}
The brain and the immune system are the two major adaptive systems of the body. During an immune response the brain and the immune system "talk to each other" and this process is essential for maintaining homeostasis. Two major pathway systems are involved in this cross-talk: the hypothalamic-pituitary-adrenal (HPA) axis and the sympathetic nervous system (SNS). This overview focuses on the role of SNS in neuroimmune interactions, an area that has received much less attention than the role of… CONTINUE READING
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human T-cell development

  • M Schwaninger, R Blume, M Kruger, G Lux, E Oetjen, W Knepel
  • Proc Natl Acad Sci USA
  • 1995
Highly Influential
8 Excerpts

Neurobiology of the intestinal mucosa

  • HJ Cooke
  • Gastroenterology
  • 1986
Highly Influential
4 Excerpts

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