The surface-located YopN protein is involved in calcium signal transduction in Yersinia pseudotuberculosis.

@article{Forsberg1991TheSY,
  title={The surface-located YopN protein is involved in calcium signal transduction in Yersinia pseudotuberculosis.},
  author={{\AA} Forsberg and A M Viitanen and Mikael Skurnik and Hans Wolf-Watz},
  journal={Molecular microbiology},
  year={1991},
  volume={5 4},
  pages={977-986}
}
The low-calcium response (Icr) is strongly conserved among the pathogenic Yersinia species and is observed when the pathogen is grown at 37°C in Ca2+ -depleted medium. This response is characterized by a general metabolic downshift and by a specific induction of virulence-plasmid-encoded yop genes. Regulation of yop expression is exerted at transcriptional level by a temperature-regulated activator and by Ca2+ -regulated negative elements. The yopN gene was shown to encode a protein (formerly… CONTINUE READING
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