The suprachiasmatic nucleus and the circadian time-keeping system revisited.

  title={The suprachiasmatic nucleus and the circadian time-keeping system revisited.},
  author={K E van Esseveldt and Michael N Lehman and G. J. Meeuwsen-de Boer},
  journal={Brain research. Brain research reviews},
  volume={33 1},
Many physiological and behavioral processes show circadian rhythms which are generated by an internal time-keeping system, the biological clock. In rodents, evidence from a variety of studies has shown the suprachiasmatic nucleus (SCN) to be the site of the master pacemaker controlling circadian rhythms. The clock of the SCN oscillates with a near 24-h period but is entrained to solar day/night rhythm by light. Much progress has been made recently in understanding the mechanisms of the… CONTINUE READING
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