The suppressor of cytokine signalling 2 (SOCS2) is a key repressor of insulin secretion


Suppressor of cytokine signalling (SOCS) proteins are powerful inhibitors of pathways involved in survival and function of pancreatic beta cells. Whereas SOCS1 and SOCS3 have been involved in immune and inflammatory processes, respectively, in beta cells, nothing is known about SOCS2 implication in the pancreas. Transgenic (tg) mice were generated that… (More)
DOI: 10.1007/s00125-010-1786-9


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