The subthalamic nucleus: From response selection to execution.

  title={The subthalamic nucleus: From response selection to execution.},
  author={Sonny K. H. Tan and Yasin Temel and Arjan Blokland and Harry W. M. Steinbusch and Veerle Visser-Vandewalle},
  journal={Journal of chemical neuroanatomy},
  volume={31 3},
The involvement of the subthalamic nucleus in physiological and pathological motor behaviour has now largely been established. Clinical observations in patients suffering from Parkinson disease treated with Deep Brain Stimulation of the STN show that these patients can suffer from postoperative changes in non-motor behaviour mainly involving alterations in cognitive functions. The involvement of the STN in cognition has initially been demonstrated by non-human studies investigating the effects… CONTINUE READING