The substrate determines the rate and pattern of neutral lipid synthesized by isolated human sebaceous glands.

@article{Middleton1988TheSD,
  title={The substrate determines the rate and pattern of neutral lipid synthesized by isolated human sebaceous glands.},
  author={Bruce Middleton and Inderpaul S Birdi and M Heffron and Joan R. Marsden},
  journal={FEBS letters},
  year={1988},
  volume={231 1},
  pages={59-61}
}
Lipogenesis from different substrates was determined in isolated human sebaceous glands after 17-20 h in culture. Rates of total lipogenesis were 1003 +/- 141, 842 +/- 90, 481 +/- 57 pmol.h-1 gland-1 +/- SE from acetate, lactate and glucose, respectively, when present as sole substrates: the rate from glucose was significantly lower (P less than 0.01). Squalene synthesis was greatest from acetate at 479 +/- 44 pmol.h-1.gland-1; significantly higher than from lactate (281 +/- 45 pmol.h-1.gland-1… CONTINUE READING