The substituted (S)-3-phenylpiperidine (−)-OSU6162 reduces apomorphine- and amphetamine-induced behaviour in Cebus apella monkeys

Abstract

Low affinity dopamine (DA) D2 antagonists such as the substituted (S)-3-phenylpiperidine (−)-OSU6162 have been proposed to be putative antipsychotic agents not endowed with extrapyramidal side effects (EPS). In the present study we investigated the effects of (−)-OSU6162 on (−)-apomorphine and d-amphetamine-induced behaviours in EPS sensitised Cebus apella… (More)
DOI: 10.1007/s00702-005-0297-1

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