The subgingival microbiome, systemic inflammation and insulin resistance: The Oral Infections, Glucose Intolerance and Insulin Resistance Study.

@article{Demmer2017TheSM,
  title={The subgingival microbiome, systemic inflammation and insulin resistance: The Oral Infections, Glucose Intolerance and Insulin Resistance Study.},
  author={Ryan T. Demmer and Alexander Breskin and Michael Rosenbaum and Aleksandra M Zuk and Charles A LeDuc and Rudolph L. Leibel and Bruce J Paster and Mo{\"i}se Desvarieux and David R. Jacobs and Panos N. Papapanou},
  journal={Journal of clinical periodontology},
  year={2017},
  volume={44 3},
  pages={
          255-265
        }
}
BACKGROUND Inflammation might link microbial exposures to insulin resistance. We investigated the cross-sectional association between periodontal microbiota, inflammation and insulin resistance. METHODS The Oral Infections, Glucose Intolerance and Insulin Resistance Study (ORIGINS) enrolled 152 diabetes-free adults (77% female) aged 20-55 years (mean = 34 ± 10). Three hundred and four subgingival plaque samples were analysed using the Human Oral Microbe Identification Microarray to measure… CONTINUE READING