The subcellular organization of Madin-Darby canine kidney cells during the formation of a polarized epithelium

  title={The subcellular organization of Madin-Darby canine kidney cells during the formation of a polarized epithelium},
  author={Robert Bacallao and Claude Antony and Carlos Dotti and Eric Karsenti and Ernst H. Stelzer and Kai Simons},
  journal={The Journal of Cell Biology},
  pages={2817 - 2832}
Studies of the developing trophectoderm in the mouse embryo have shown that extensive cellular remodeling occurs during epithelial formation. In this investigation, confocal immunofluorescence microscopy is used to examine the three-dimensional changes in cellular architecture that take place during the polarization of a terminally differentiated epithelial cell line. Madin-Darby canine kidney cells were plated at a low density on permeable filter supports. Antibodies that specifically… CONTINUE READING
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