The subcallosal cingulate gyrus in the context of major depression.

@article{Hamani2011TheSC,
  title={The subcallosal cingulate gyrus in the context of major depression.},
  author={Clement Hamani and Helen S. Mayberg and Scellig S. Stone and Adrian W. Laxton and Suzanne N. Haber and Andres M. Lozano},
  journal={Biological psychiatry},
  year={2011},
  volume={69 4},
  pages={301-8}
}
The subcallosal cingulate gyrus (SCG), including Brodmann area 25 and parts of 24 and 32, is the portion of the cingulum that lies ventral to the corpus callosum. It constitutes an important node in a network that includes cortical structures, the limbic system, thalamus, hypothalamus, and brainstem nuclei. Imaging studies have shown abnormal SCG metabolic activity in patients with depression, a pattern that is reversed by various antidepressant therapies. The involvement of the SCG in… CONTINUE READING