The study of p53 and p16 immunoexpression in serous borderline and malignant ovarian tumors.

@article{Marias2012TheSO,
  title={The study of p53 and p16 immunoexpression in serous borderline and malignant ovarian tumors.},
  author={M. Mari{\~n}as and Dan Gabriel Mogoş and Cristiana Eugenia Simionescu and Al. Stepan and Florentina Tănase},
  journal={Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie},
  year={2012},
  volume={53 4},
  pages={1021-5}
}
The study assessed p53 and p16 immunoexpression in 20 cases of ovarian serous carcinomas and four cases of serous borderline tumors, the results being statistically analyzed in relation to clinicopathological data of the cases. The p53 immunoreaction was observed in 85% of cases, the medium percentage of positivity being 15% for borderline tumors, 45% for low-grade carcinomas and 60% for high-grade carcinomas. The p16 immunoreaction was observed in 75% of cases, the medium percentage of… CONTINUE READING