Visualization of Tegument-Capsid Interactions and DNA in Intact Herpes Simplex Virus Type 1 Virions
- BiologyJournal of Virology
Herpes simplex virus type 1 virions were examined by electron cryomicroscopy, allowing the three-dimensional structure of the infectious particle to be visualized for the first time, suggesting a spool model for DNA packaging, similar to that for some bacteriophages.
Cytochemical Reactions of Nucleic Acids
- BiologyThe Quarterly Review of Biology
The purpose of this paper is to review the most pertinent literature concerning the cytochemical techniques for studying the nucleic acids and to discuss their validity as specific tests.
- Genome Chaos
The “scientific catastrophe” in nucleic acids research that boosted molecular biology
- BiologyThe Journal of Biological Chemistry
The distinctive profile of the double-helix DNA molecule is today, along with Rutherford’s depiction of the atom as a miniature planetary system, a worldwide-recognized symbol of twentieth-century…
The discovery of hydrogen bonds in DNA and a re-evaluation of the 1948 Creeth two-chain model for its structure
- BiologyBiochemical Society transactions
Analysis of Creeth's model of DNA structure shows that his incorporation of alternating breaks in the two-chain structure was not necessary to explain the viscosity data on scission of hydrogen bonds after titrating to high or low pH, and a tentative model for DNA proposed by Gulland's and D.O.Gulland is considered.
A Speculative History of DNA: What If Oswald Avery Had Died in 1934?
- BiologyPLoS biology
This speculative Essay explores the consequences of the imagined premature death of Oswald Avery, who in 1944 provided evidence that genes are made of DNA. Four imaginary alternate routes to the…
Oswald Avery, DNA, and the transformation of biology
- HistoryCurrent Biology