The structure of the nuclear hormone receptors.

  title={The structure of the nuclear hormone receptors.},
  author={Raj Kumar and E Brad Thompson},
  volume={64 5},
The functions of the group of proteins known as nuclear receptors will be understood fully only when their working three-dimensional structures are known. These ligand-activated transcription factors belong to the steroid-thyroid-retinoid receptor superfamily, which include the receptors for steroids, thyroid hormone, vitamins A- and D-derived hormones, and certain fatty acids. The majority of family members are homologous proteins for which no ligand has been identified (the orphan receptors… CONTINUE READING
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Molecular basis of agonism and antagonism in the oestrogen receptor

  • AM Brzozowski, ACW Piki, +7 authors M. Carlquist
  • Nature
  • 1997
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  • B Ducouret, M Tujague, +4 authors EB. Thompson
  • Endocrinol
  • 1995
Highly Influential
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Purification and characterization of the C-terminal transactivation domain of Vmw65 from herpes simplex virus type I

  • L Donaldson, JP Capron
  • J Biol Chem 1992;267(3):1411–14
  • 1999
1 Excerpt

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