The structure of the KlcA and ArdB proteins reveals a novel fold and antirestriction activity against Type I DNA restriction systems in vivo but not in vitro

@inproceedings{SerfiotisMitsa2010TheSO,
  title={The structure of the KlcA and ArdB proteins reveals a novel fold and antirestriction activity against Type I DNA restriction systems in vivo but not in vitro},
  author={Dimitra Serfiotis-Mitsa and Andrew Herbert and G. A. Roberts and Dinesh C Soares and J. A. Henton White and Garry W. Blakely and Du{\vs}an Uhr{\'i}n and David T. F. Dryden},
  booktitle={Nucleic acids research},
  year={2010}
}
Plasmids, conjugative transposons and phage frequently encode anti-restriction proteins to enhance their chances of entering a new bacterial host that is highly likely to contain a Type I DNA restriction and modification (RM) system. The RM system usually destroys the invading DNA. Some of the anti-restriction proteins are DNA mimics and bind to the RM enzyme to prevent it binding to DNA. In this article, we characterize ArdB anti-restriction proteins and their close homologues, the KlcA… CONTINUE READING
10 Citations
78 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 10 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 78 references

Similar Papers

Loading similar papers…