The structure of the E. coli recA protein monomer and polymer

@article{Story1992TheSO,
  title={The structure of the E. coli recA protein monomer and polymer},
  author={Randall M. Story and Irene T. Weber and Thomas A Steitz},
  journal={Nature},
  year={1992},
  volume={355},
  pages={318-325}
}
The crystal structure of the recA protein from Escherichia coli at 2.3-Å resolution reveals a major domain that binds ADP and probably single- and double-stranded DNA. Two smaller subdomains at the N and C termini protrude from the protein and respectively stabilize a 61 helical polymer of protein subunits and interpolymer bundles. This polymer structure closely resembles that of recA/DNA filaments determined by electron microscopy. Mutations in recA protein that enhance coprotease, DNA-binding… CONTINUE READING
Highly Influential
This paper has highly influenced 23 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 174 extracted citations

A Dna Helicase from Saccharomyces Cerevisiae Mitochondria

DISSERTATIONES BIOLOGICAE UNIVERSITATIS TARTUENSIS
2006
View 5 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…