The structure of the ATPase that powers DNA packaging into bacteriophage T4 procapsids.

@article{Sun2007TheSO,
  title={The structure of the ATPase that powers DNA packaging into bacteriophage T4 procapsids.},
  author={Siyang Sun and Kiran Kondabagil and Petra M Gentz and Michael G. Rossmann and Venigalla Rao},
  journal={Molecular cell},
  year={2007},
  volume={25 6},
  pages={943-9}
}
Packaging the viral genome into empty procapsids, an essential event in the life cycle of tailed bacteriophages and some eukaryotic viruses, is a process that shares features with chromosome assembly. Most viral procapsids possess a special vertex containing a dodecameric portal protein that is used for entry and exit of the viral genome. The portal and an ATPase are parts of the genome-packaging machine. The ATPase is required to provide energy for translocation and compaction of the negative… CONTINUE READING