The structure of the ASAP core complex reveals the existence of a Pinin-containing PSAP complex

Abstract

The ASAP complex interacts with the exon-junction complex (EJC), a messenger ribonucleoprotein complex involved in post-transcriptional regulation. The three ASAP subunits (Acinus, RNPS1 and SAP18) have been individually implicated in transcriptional regulation, pre-mRNA splicing and mRNA quality control. To shed light on the basis for and consequences of… (More)
DOI: 10.1038/nsmb.2242

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