The structure of cyanine 5 terminally attached to double-stranded DNA: implications for FRET studies.


Fluorescence resonance energy transfer, FRET, can be used to obtain long-range distance information for macromolecules and is particularly powerful when used in single-molecule studies. The determination of accurate distances requires knowledge of the fluorophore position with respect to the macromolecule. In this study we have used NMR to determine the… (More)
DOI: 10.1021/bi800773f


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