The structure of aconitase

@article{Robbins1989TheSO,
  title={The structure of aconitase},
  author={Arthur Robbins and Charles David Stout},
  journal={Proteins: Structure},
  year={1989},
  volume={5}
}
The crystal structure of the 80,000 Da FeS enzyme aconitase has been solved and refined at 2.1 Å resolution. The protein contains four domains; the first three from the N‐terminus are closely associated around the [3Fe–4S] cluster with all three cysteine ligands to the cluster being provided by the third domain. Associationof the larger C‐terminal domain with the first three domains createsan extensive cleft leading to the FeS cluster. Residues from all four domains contribute to the active… 

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    Proceedings of the National Academy of Sciences of the United States of America
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