The structure of a redundant enzyme: a second isoform of aspartate beta-semialdehyde dehydrogenase in Vibrio cholerae.

@article{Viola2008TheSO,
  title={The structure of a redundant enzyme: a second isoform of aspartate beta-semialdehyde dehydrogenase in Vibrio cholerae.},
  author={Ronald E. Viola and Xuying Liu and Jeffrey F Ohren and Christopher R Faehnle},
  journal={Acta crystallographica. Section D, Biological crystallography},
  year={2008},
  volume={64 Pt 3},
  pages={321-30}
}
Aspartate-beta-semialdehyde dehydrogenase (ASADH) is an essential enzyme that is found in bacteria, fungi and plants but not in humans. ASADH produces the first branch-point metabolite in the biosynthetic pathways that lead to the production of lysine, threonine, methionine and isoleucine as well as the cell-wall precursor diaminopimelate. As a consequence… CONTINUE READING