The structure of a plasmid of Chlamydia trachomatis believed to be required for growth within mammalian cells.

@article{Comanducci1988TheSO,
  title={The structure of a plasmid of Chlamydia trachomatis believed to be required for growth within mammalian cells.},
  author={Maurizio Comanducci and S. Ricci and Giulio Ratti},
  journal={Molecular microbiology},
  year={1988},
  volume={2 4},
  pages={
          531-8
        }
}
Sequence analysis of a 7.5 kb DNA plasmid isolated from Chlamydia trachomatis shows 8 open reading frames (ORFs) regularly spaced along most of the sequence. One of these ORFs encodes a 451-amino-acid polypeptide highly homologous to the DnaB protein of Escherichia coli. A region between ORFs 6 and 7 contains a cluster of alternating ATs and a 22 bp sequence tandemly repeated 4 times, suggesting a replication control region. Several ORFs correspond to plasmid-specific polypeptides that have… CONTINUE READING
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