The structure of Rv2372c identifies an RsmE-like methyltransferase from Mycobacterium tuberculosis.

Abstract

U1498 of 16S rRNA plays an important role in translation fidelity as well as in antibiotic response. U1498 is present in a methylated form in the decoding centre of the ribosome. In this study, Rv2372c from Mycobacterium tuberculosis has been identified as an RsmE-like methyltransferase which specifically methylates U1498 of 16S rRNA at the N3 position and… (More)
DOI: 10.1107/S1399004713033555

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