The structure and function of the retromer protein complex.

  title={The structure and function of the retromer protein complex.},
  author={Brett M Collins},
  volume={9 11},
The transport of transmembrane proteins and associated ligands through the endosomal system is governed by a number of different protein assemblies. One such assembly is retromer, a peripheral membrane protein complex that has important roles in endosomal sorting of a variety of cargo molecules. Retromer was first shown to control the endosome-to-Golgi retrieval of lysosomal hydrolase receptors, and over the past few years, it has been found to play a similar role in the transport of many other… CONTINUE READING

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