The structure and allosteric regulation of glutamate dehydrogenase.


Glutamate dehydrogenase (GDH) has been extensively studied for more than 50 years. Of particular interest is the fact that, while considered by most to be a 'housekeeping' enzyme, the animal form of GDH is heavily regulated by a wide array of allosteric effectors and exhibits extensive inter-subunit communication. While the chemical mechanism for GDH has… (More)
DOI: 10.1016/j.neuint.2010.10.017


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