The structural protein p54 is essential for African swine fever virus viability.

@article{Rodrguez1996TheSP,
  title={The structural protein p54 is essential for African swine fever virus viability.},
  author={Fernando Rodr{\'i}guez and Victoria Ley and Paulino G{\'o}mez-Puertas and R {\'A}-F Garc{\'i}a and Jos{\'e} Francisco Rodr{\'i}guez and Jos{\'e} M. Escribano},
  journal={Virus research},
  year={1996},
  volume={40 2},
  pages={161-7}
}
Protein p54, one of the most antigenic structural African swine fever virus (ASFV) proteins, has been localized by immuno-electron microscopy in the replication factories of infected cells, mainly associated with membranes and immature virus particles. Attempts to inactivate the p54 gene from ASFV by targeted insertion of beta-galactosidase selection marker was uniformly unsuccessful, suggesting that this gene is essential for virus viability. To demonstrate that, we inserted in the TK… CONTINUE READING

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