The structural organization of DNA packaged within the heads of T4 wild-type, isometric and giant bacteriophages.

@article{Earnshaw1978TheSO,
  title={The structural organization of DNA packaged within the heads of T4 wild-type, isometric and giant bacteriophages.},
  author={William C Earnshaw and Jonathan King and Stephen C Harrison and Frederick A. Eiserling},
  journal={Cell},
  year={1978},
  volume={14 3},
  pages={559-68}
}
We present electron microscopic and X-ray diffraction evidence concerning the structural organization of condensed DNA within a series of T4 bacteriophage with the following head morphologies: prolate (wild-type), isometric and giant (with greatly increased axial ratio). In all cases, the DNA helix segments are locally parallel and 27 A apart. For the giant particles, we show that the DNA forms a large coil whose axis is perpendicular to the axis of the phage tail. This evidence, combined with… CONTINUE READING
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