The structural dynamics of α-tropomyosin on F-actin shape the overlap complex between adjacent tropomyosin molecules.

Abstract

Coiled-coil tropomyosin, localized on actin filaments in virtually all eukaryotic cells, serves as a gatekeeper regulating access of the motor protein myosin and other actin-binding proteins onto the thin filament surface. Tropomyosin's modular pseudo-repeating pattern of approximately 39 amino acid residues is designed to allow binding of the coiled-coil… (More)
DOI: 10.1016/j.abb.2013.09.011

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@article{Lehman2014TheSD, title={The structural dynamics of α-tropomyosin on F-actin shape the overlap complex between adjacent tropomyosin molecules.}, author={William Lehman and Xiaochuan Li and Marek Orzechowski and Stefan Fischer}, journal={Archives of biochemistry and biophysics}, year={2014}, volume={552-553}, pages={68-73} }